Cathepsin Inhibitor 1 - Search Results

About 7 results found for searched term "Cathepsin Inhibitor 1" (0.268 seconds)

Cat.No.	Name	Target
M2497	Cathepsin Inhibitor 1	Cathepsin
	Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
M14307	LY 3000328	Cathepsin
	LY 3000328 is a potent and selective Cathepsin S (Cat S) inhibitor with IC50s of 7.7 and 1.67 nM for hCat S and mCat S, respectively.
M20881	2-cyano-Pyrimidine	Others
	2-cyano-Pyrimidine is a cathepsin K inhibitor with an IC50 of 170 nM.
M28225	MIV-247	Cathepsin
	MIV-247 is a selective cathepsin S inhibitor with Kis of 2.1, 4.2 and 7.5 nM for human, mouse and cynomolgus monkey cathepsin S, respectively.
M30349	L-873724	Cathepsin
	L-873724 is a potent, orally bioavailable, selective and reversible[2] non-basic cathepsin K inhibitor, with IC50s of 0.2, 178, 264, and 5239 nM for cathepsin K, cathepsin S, cathepsin L, cathepsin B, respectively. L-873724 also exhibits an IC50 of 0.5 nM for rabbit cathepsin K. L-873724 inhibits bone resorption.
M30755	ONO-5334	Cathepsin
	ONO-5334 is a potent, selective and orally active cathepsin K inhibitor with Ki values of 0.10 nM, 0.049 nM and 0.85 nM for human, rabbit and rat cathepsin K, respectively. ONO 5334 is an effective antiviral compound against SAR-COV-2 virus activity with an EC50 value of 500 nM. ONO-5334 has the potential for the study of osteoporosis and COVID-19 disease.
M42905	Cathepsin Inhibitor 3	Others
	Cathepsin Inhibitor 3 is a non-radioactive intermediate in compound [18F] 2k radioactive synthesis, which has selectivity for cathepsin S.